In "Wii - Glee Karaoke Revolution," players sing along to songs from the TV show "Glee." The gameplay involves selecting a song, following the on-screen lyrics, and using the Wii Remote to match pitch and timing. Players are scored based on their performance accuracy, with feedback provided after each song. The game offers various modes, including solo, duet, and multiplayer options, making it suitable for both solo play and social gatherings. It's an entertaining way for fans of "Glee" to showcase their vocal skills and enjoy karaoke-style fun.